C344 Embryology, Anatomy, and Function of the Esophagus

C344.1 Common Clinical Manifestations and Diagnostic Aids
C345 Congenital Anomalies
C345.1 Esophageal Atresia and Tracheoesophageal Fistula

Presentation
????? ??, ?? ?? ? ???, choking, coughing, and regurgitation with initial feeding attempts
?? ??? ??
O : ????
X : airless abdomen
H : ???? ??, ??? ??
Diagnosis
Prox. Atresia w/ distal TEF : m/c
Management
- ??? ?? XR, ???? ??.
- Aspiration pneumonia ?? ?? L-tube? ????.
- Extrapleural thoracotomy (through Rt 4th ICS)

Surgery
- ?? ?
- Prone position
- ???? ?? – ????? ??
- Preop echocardiogram ->aortic arch ?? ?? (????? ?? ????? ?? ??)
Outcome
????(50%) ?? – VACTERL
Vertebral, Anerectal, Cardiac, Tracheal, Esophageal, Renal, Limb
C345.2 Laryngotracheoesophageal Clefts
C345.3 Congenital Esophageal Stenosis
C346 Obstructing and Motility Disorders of the Esophagus
Extrinsic
Esophageal duplication cysts
Neuroenteric cysts
Vertebral anomalies
Enlarged mediastinal or subcarinal lymph nodes
Vascular anomalies
Intrinsic
Schatzki ring
Eosinophilic esophagitis
C347 Dysmotility
Achalasia
??? air-fluid level, ????? bird-beak ? ??? ?? (?? ??)
TOC : Ballon dilatation / ??? : Heller esophagomyotomy
C348 Hiatal Hernia
C349 Gastroesophageal Re?ux Disease
4?? ? ?, ???? ??? ????? ?? ??
?? : ???? 24hr pH test (?? ???)
?? : ? ?? ?? ???, ? ? ?? ? ?????
?? : PPI, H2 blocker, erythromycin, metoclopromide (??? ?? ??)
?? : Nissel fundoplication (??? ??, ??? ???)
Differential diagnosis: infant regurgitation
C349.1 Complications of Gastroesophageal Reflux Disease
C350 Eosinophilic Esophagitis, Pill Esophagitis, and Infective Esophagitis
Eosinophilic esophagitis
- Pathogenesis
- Chronic, immune-mediated esophageal inflammation
- Triggered by food allergens
- Clinical features
- Dysphagia, chest/epigastric pain, reflux/vomiting, solid food impaction
- Eczema or other allergic conditions (eg, asthma, rhinitis)
- Diagnosis
- 2-month trial of PPI therapy as diagnostic evaluation
- If there is no improvement, …
- Endoscopy: The eosinophilic esophagitis endoscopic reference score (EREFS), based on commonly observed features of edema (E), rings (R), exudates (E), furrows (F), strictures (S)
- Esophageal biopsy: >15 eosinophils per HPF
- Circular rings and esophageal furrows are nonspecific findings.
- Treatment
- Dietary modification to avoid potential food triggers.
- Topical (eg, swallowed) fluticasone

FIG. 350.1
Endoscopic visualization of esophageal food impaction (yellow arrow) and mucosal rings (blue arrows) .
FIG. 350.2 Endoscopic image of eosinophilic esophagitis with characteristic mucosal appearance of furrowing and white specks. 
FIG. 350.3 Endoscopy photograph showing mucosal furrowing (blue arrows) characteristic of Eosinophilic esophagitis in a patient with food impaction (yellow arrow) .
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