🇨 H&N

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6th m/c, 90% SqCC
Elderly men exposed to smoking, alcohol abuse, EBV/HPV

Constraints

Esophagus 는 60Gy 이상 들어가면 안될 것.

RO de-escalation/hypofx

NCCN Guideline – Skin SqCC

Anatomy, epidemiology, staging

Management

Constituentsmucosal lipbuccal mucosaalveolar ridges
retromolar trigonefloor of mouthhard palateoral tongue (anterior 2/3)

Constituentsbase of tongue (BOT)tonsillar complexsoft palatePPW

Epidemiology to staging

Management Strategies

  • T1: 66Gy/33Fx
  • Stage 1-2: 70Gy/35Fx
  • Stage 3-4: CCRT w/ cisplatin 100mg/m2 q 3wks
  • T4 or N3: induction chemo
  • Neck dissection in only PET positive ~ wks

Anatomy, Epidemiology, Staging

Management Strategies

Tumor stageRecommendations
Stage IRT alone or voice preservation surgery if feasible
Stage IIRT alone
Stage III & IV with functional laryngopharynxCCRT followed by SND
Stage III & IV with dysfunctional laryngopharynxaLaryngopharyngectomy with adjuvant RT or CRT
aPatients with bulky, destructive tumors that severely compromise the airway or destroy cartilage, bone, and deep soft tissue are often best served with immediate laryngopharyngectomy and postoperative radiation or chemoradiation.

Management