Medical Archive

Introduction

Etiologic agent

Epidemiology

Pathogenesis and pathology

Clinical manifestations

• ??? 1-4?
• ??, ??, ??, ??? ?? -> mucoid & bloody diarrhea, tenesmus
• ?? ??
  • ??? (m/c): ??, ????, encephalopathic Sx
  • Hemolytic-uremic syndrome (HUS)
  • Reactive arthritis, Reiter’s syndrome

Laboratory diagnosis

• Stool culture
  • Shigella ??
  • Bloody & mucus, PMN ??

Treatment

Antibiotic susceptibility of Shigella

Antibiotic treatment of Shigellosis

• 1st line – ciprofloxacin
  • Adult: 500mg, child: 15mg/kg
  • 2 times per day for 3 days, PO
• 2nd line
  • Pivmecillinam
  • Ceftriaxone
  • Azithromycin

Rehydration and nutrition

Nonspecific, symptom-based treatment

Treatment of complications

Prevention