C36 Thyroid

Historical Perspective

Anatomy

Physiology of the Thyroid Gland

Disorders of Thyroid Metabolism — Benign Thyroid

Disease Evaluation of a Thyroid Nodule

Thyroid Malignancies

Thyroid oncogenesis

Papillary thyroid carcinoma

Follicular thyroid carcinoma

Treatment of differentiated thyroid carcinoma (papillary and follicular)

  • Lobectomy + isthmusectomy
    • 1cm ??, ???? ???? ipsilateral, ?? ??? ???(-)? ?? ??.
    • 1~2cm? ?? total hyroidcectomy? ?? ?? ??.
  • Total thyroidectomy
    • LN(-): ?? ? ?? ?? + central LND
    • LN(+): ?? ? ?? ?? + modified LND

Medullary thyroid carcinoma

Treatment

Total ± CND (sporadic/MEN ??? ???)

Poorly differentiated thyroid carcinoma

Anaplastic thyroid carcinoma

Thyroid Disease in Pregnancy

Surgical Approaches to the Thyroid

Standard cervical thyroidectomy

  • PTC?? ?? ???? ???? ??
    • ?? ??? ??.
    • ?? ? ?????? ??? ??? ? ??? ??
    • 131I ???? ? TG ??? ????? ??.

Postop management

  1. 3?? liothyronine(T3) ??
  2. T3 ?? TSH ???? 3-4? ???
  3. 131I scan (5-10mCi) – ???? ???? ?? ??
  4. 131I ?? ?? ??? ablation
    1. Indication: ????, ???? ???? ??, ?? ???? ??? ?? 4cm ??? ??.

Follow up

?? ??: lung, bone

  • Serology
    • Thyroglobulin level: Tg with TSH titer, anti-Tg Ab titer
    • Calcitonin (medullary ca.)
  • 131I whole body scan (?? ? 6?? ?)
    • ??? ??: 1? ? ???
    • ??? ??: T4 suppression therapy ??? 6-12???? TG ??.
    • ??: therapeutic 131I.
  • Neck sono
  • PET ? ?? ??? ????? ??? scan.

Lateral neck dissection

Substernal goiter

Alternative approaches to thyroid surgery

Complications of thyroid surgery

  • Hematoma
    • airway obstruction -> immediately wound open, drainage
  • Recurrent laryngeal nerve
    • ???? Permanent hoarsness
    • Simmon’s triangle: Common carotid a. & inf. Thyroid a.? ?? ??? 
    • T-E groove? ???, aorta? ?? (Lt.)
    • Rt. Subclavian a.? ??? non-recurrent? ????
  • Superior laryngeal nerve
    • To cricothyroid muscle, ext./int.
    • Superior pole ??? ? ?? ?? ??? ??
    • ???? loss of high tone voice quality
  • CN11 – Winged scapula
  • Brachial plexus – ?? ??
  • Horner’s SD – Sympathetic truck ??
  • Chyle leakage
    • Thoracic duct injury – ??? ?? ??
    • 500ml/day ??? ? surgical intervention

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