Medical Archive

??

K760 NASH

K80.50 ??? or ?? ??

?????

???(UDCA) 100mg

?? ??

1. AST or ALT >60U/L
2. AST or ALT 40~60U/L? ??, 3?? ?? >40U/L ???? ??
3. AST or ALT <40U/L???? ??? ??? ?? ??? ?? ???? ??.
4. ??/??? ??? ??? ????? ??? ?? ??.

???(UDCA) 200mg

??? ?? ??? 100mg ??? ??. ???… Gallstone, CHC ?? ?? ? ????? ?.

??? Godex cap. (?) ????

???? ????? ???? ??. ??????? ?? ??? 1??? ???? ??.

1/2/15? ??, ??? ?? ?? ?? ???? ??.

Adenine HCl 2.5mg

Biphenyl Dimethyl Dicarboxylate 25mg

Carnitine orotate 150mg

Vitamin B (Riboflavin 0.5mg, Pyridoxine Hydrochloride 25mg, Cyanocobalamin 0.125mg

Liver Extract Antitoxic fraction 12.5mg

???? (?) ?????

Biphenyl Dimethyl Dicarboxylate 25mg

1/2/15? ???? ?? ???? ?? ?. (?? ??? 1~2/3/15)

?????

??? ? Ganezin (?) ????

???? ?? ?? ??. Biphenyl Dimethyl Dicarboxylate (BDD)? ??? ??? ??? 2?? ???.

??? ?? (?) ????

L-arginine 7.31g

?????? 5.00g

??? 5.00g

citrate 2.94g

???? ????

L-arginine HCl 120mg

L-ornithine HCl 60mg

L-citrulline 60mg

?????

L-asparaginate-L-ornithine

?? ?? ? ornithine? asparaginate? ???? ??.

???????

?? ??(????)

HCV?? ??? ??? ? ??? ???.

??? ??? ??? ???? ?? ?? ??? ? ?.

? ?? Review

L-carnitine

??, ?, ??? ?? ??. .

??? ??? lysine, methionine? ??? ???? ?? ?? ?? ??? ?? ??.

?? 20-200mg ??? ????, ?????? 1,000mg ??? ????? ?.

Physiology

1. ??? androgen receptor ? ??? ??, ??? ???? ??
2. ???? ?? ??? ???? ??? ????? ?? (carnitine shuttle)
3. ?? ?? ROS? ???? ??? ??? ?? ????? ??.

???? ?????? ??? ?.

Carnitine orotate

L-carnitine? bioavailability? ?? ?.

NAFLD??? NIDDM??? ???, ???, HbA1c ???? ??? ??.

? ?? ??? (???, ???)? ??????.

Acetyl L-carnitine

Bioavailability? ?????? ??, BBB?? ????? ?? ??.

????? ????? ??? ?? acetylcholine??? ??

? ? ?? ???? ?? (???, ???, ???)

Arginine

Urea cycle? ?? ammonia? ??? ?????? ??.

Urea cycle? ???? ornithine? citrulline? ?? ??? ? ??? ??.

Betain, lecithine, choline, methionine

Betain

??? ????? ??? ??? ??. ? ? ?? ?? ??, ??? ?? ??.

Homocystein? methyl?? ???? methionine?? ? ? ??? ??? ??

Choline

???? betain?? ????.

Lecithine

Choline???? ??, ????? ??? ?? ??? ??.

?? ?? ? ????, ????? ??.

????? ?? ??? ?? ??? ????.

Methionine

Glutathione ??? ??? ??. Betain?? ?? methyl?? ???.

Methionine ? homocystein ? cystein ? glutathione

Biphenyl Dimethyl Dicarboxylate (DBB)

Pros

1. Cytochrome P450B ? ???? ??? ?? ? ???? ??
2. (HCV?????) AST, ALT, ALP, GGT, Bilirubin ?? ??? ???? ??? ???.

Cons

1. ?? ????? ??? ??? ??? ALT ?? ??? ????? ???? ???.