Medical Archive

Primary Management – Respiratory

?: up regulation of NMDA receptor
? antagonizes NMDA glutamate receptors

??? ??
- Narcotic opioids
  - Morphine, codeine, hydrocodone
  - ???? ?? ??, ??, ??, ????, ??
- Non-narcotic opioids
  - Dextromethrophan; weak NMDA antagonist
- Nonopioids
- ??????: dextromethorphan + ephedrine + pheniramine
- ????: dextromethorphan ?? codeine -> ?? ?? ??.
- ?????: ??? codeine + guaifenesin
??? ??
- Levodropropizine ????, ?? ?? ? C-fiber ??.
  24?? ?? ???, ?? ??? ?? ? ??
- Guaifenesin ?? ???? ??. ?? ?? ????? ??? ?? ??? ???? ??.
? ?
- 1?? ?????
  - CNS ????, ????? ??.
- ???? (e.g., ipratropium bromide ???)

An agent that induces discharge or expulsion of mucus from the respiratory tract

Hypertonic saline
Iodine-containing compounds
Guaifenesin (glyceryl guaiacolate)
Bromhexine
Ion channel modifiers
- Tricyclic nucleotides
  - Regulate ion transport through P2Y2 purinergic receptors that increase intracellular calcium
- Nebulised uridine triphosphate aerosol

Drugs that regulate mucus secretion or interfere with the DNA/F-actin network

Liquifies mucus by disrupting disulfide bonds.

The majority of mucokinetic agents (sometimes referred to as cough clearance promoters) increase mucociliary clearance by acting on the cilia.

??: qd, 10? ??: bid, 5?

JX999 ?? ??

Mometasone furoate 60?, 140? ? ??????